Effects of parathyroid hormone on delayed renal allograft function.
نویسندگان
چکیده
منابع مشابه
Effects of Parathyroid Hormone on Immune Function
Parathyroid hormone (PTH) function as immunologic mediator has become interesting with the recent usage of PTH analogue (teriparatide) in the management of osteoporosis. Since the early 1980s, PTH receptors were found on most immunologic cells (neutrophils, B and T cells). The in vitro evaluations for a possible role of PTH as immunomodulator have shown inconsistent results mainly due to method...
متن کاملMajor effects of delayed graft function and cold ischaemia time on renal allograft survival.
BACKGROUND There is mounting evidence from experimental and clinical studies that the quality of organs from cadaver donors may be influenced by events occurring around the time of brain death, and that these may affect transplant outcome. The aim of this study is to investigate the influence of donor factors on renal allograft outcome in a homogeneous cohort of 518 patients transplanted in a s...
متن کاملThe effects of parathyroid extract on renal function in man.
The evidence that parathyroid extract acts directly on bone appears conclusive (1-3). Whether the extract exerts an effect on the kidney, however, has not been so convincingly answered. It has long been known that an increase in urinary phosphate follows the administration of parathyroid extract (4, 5), but the mechanism of the phosphaturia has not been clearly elucidated. Although the osteocla...
متن کاملEffects of acute and chronic hypercalcemia on parathyroid function and circulating parathyroid hormone molecular forms.
Bas et al. (1), in this issue, have demonstrated that acute hypercalcemic clamp over 2 h in rabbits reduces the subsequent intact (I) parathyroid hormone (PTH) response to hypocalcemia by 50%, while chronic hypercalcemia, secondary to experimental renal failure in the same animal model, fails to reduce the I-PTH response to hypocalcemia. These results raise questions about the acute and chronic...
متن کاملEffects of Parathyroid Hormone on Osteoblast Differentiation
It has been reported that PTH exerts bone-forming effects in vivo when administered intermittently. In the present study, the anabolic effects of PTH(1-34) on osteoblast differentiation were examined in vitro. Osteoblastic cells isolated from newborn rat calvaria were cyclically treated with PTH(1-34) for the first few hours of each 48-h incubation cycle. When osteoblastic cells were intermitte...
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ژورنال
عنوان ژورنال: BMJ
سال: 1991
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.303.6797.287